Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride ( —— )

产品货号. M27021 CAS No. 2376990-30-4

沙利度胺-O-酰胺基-PEG2-C2-NH2 盐酸盐包含 E3 连接酶配体和接头。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
5MG	￥567	有现货
10MG	￥794	有现货
25MG	￥1393	有现货
50MG	￥2373	有现货
100MG	￥3993	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

沙利度胺-O-酰胺基-PEG2-C2-NH2 盐酸盐包含 E3 连接酶配体和接头。
产品描述

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker. Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride can be used as an immunomodulator for the treatment of cancer.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
体外实验

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
体内实验

——
同义词

——
通路

Others
靶点

Other Targets
受体

——
研究领域

——
适应症

——

化学信息

CAS Number

2376990-30-4
分子量

498.92
分子式

C21H27ClN4O8
纯度

>98% (HPLC)
溶解度

——
SMILES

Cl.NCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
化学全称

——

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1.Uemura M, et al. An in vivo highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex largely circumvents in vitro cisplatin resistance: two linkage isomers yield the same product upon reaction with 9-ethylguanine but exhibit different cytotoxic profiles. Metallomics. 2012 Jul;4(7):686-92.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册